产品推荐：1-乙基-5-(硼酸频哪醇酯-2-基)吡啶-2(1H)-酮（1349734-00-4）

2021/6/2 14:24:19
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名称：1-乙基-5-(硼酸频哪醇酯-2-基)吡啶-2(1H)-酮

英文名称：1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one

分子式：C13H20BNO3

分子量: 249.11
Cas No.：1349734-00-4
结构式：

规格：95%

用途：基础原料、有机中间体、医药中间体

合成路线如下：

(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; 1,4-dioxane;

Reactants are commercially availlable.
CHAN, Katrina, US2013/53362, A1, (2013) [0999] To a suspension of ? 5-bromo-1-ethylpyridin-2(1H)-one (250 mg, 1.23 mmol) in ? 1,4-dioxane (15 mL), 4,4,4?,4?,5,5,5?,5?-octamethyl-2,2?-bi( ? 1,3,2-dioxaborolane (346.4 mg, 1.35 mmol), ? 1 ,1?-bis(diphenyl phosphino)ferrocene]dichloropalladium(II) (100 mg, 0.12 mmol) and ? potassium ace tate (301.4 mg, 3.08 mmol) were added. The reaction mixture was stirred at reflux for 3 h. The resu lting mixture was concentrated in vacuo, and the residue was purified by column chromatography on silica gel (10-101)'0 PE-AE) to afford ? 1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyr idin-2(1H)-one

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名称：1-乙基-5-(硼酸频哪醇酯-2-基)吡啶-2(1H)-酮

英文名称：1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one

分子式：C13H20BNO3