【人名反应】Fleming-Kumada氧化反应

烷基硅烷用过氧酸被立体选择性地氧化为相应的烷基醇。

反应机理

反应实例

参考文献

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(b) Fleming, I.; Sanderson, P.E. J. Tetrahedron Lett. 1987, 28, 4229􀀐4232. (c)Fleming,

I.; Dunoguès, J.; Smithers, R. Org.React. 1989, 37, 57-576. (Review).

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J. Org. Chem. 1999, 64, 6005-6018.

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6. Lee, T. W.; Corey, E. J. Org.Lett. 2001, 3, 3337-3339.

7. Jung, M. E.; Piizzi, G. J.Org. Chem. 2003, 68, 2572-2582.

8. Paquette, L. A.; Yang, J.;Long, Y. O. J. Am. Chem. Soc. 2003, 125, 1567-1574.

9. Clive, D. L. J.; Cheng, H.;Gangopadhyay, P.; Huang, X.; Prabhudas, B. Tetrahedron

2004, 60, 4205-4221.

10. Mullins, R. J.; Jolley, S.L.; Knapp, A. R. Tamao–Kumada–Fleming Oxidation. In

Name Reactions forFunctional Group Transformations; Li, J. J.,Ed.; Wiley: Hoboken,

NJ, 2007, pp237-247. (Review).

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