规格：95%
外观：棕色固体
用途：基础原料、有机中间体、医药中间体
合成工艺如下：
N-chloro-succinimide; dibenzoyl peroxide; tetrachloromethane;
Reactants are commercially availlable.
Tabart, Michel, US2002/22631, A1, (2002) 5-Chloromethylthiazole: 11 g of N-chloro-succinimide are added to a solution of 8.2 g of 5-methylthiazole in 250 cm3 of carbon tetrachloride, followed by addition of 0.1 g of benzoyl peroxide. The mix ture is heated for 20 hours at a temperature in the region of 80°C. and is then exposed to UV for 5 hours. The reaction mixture is cooled, filtered and concentrated under reduced pressure (1 kPa) at a temperature in the region of 20°C. 6.4 g of 5-chloro-m ethylthiazole are obtained [Mass spectrum: DCI m/z=134 MH+]
Feel free to call us on
025-85998075
Drop us a line anytime at
sales@popebiotech.com,
and we’ll get back
soon.
Come visit us at 2 Qiande Road, Life Science High Tech Zone, Jiang Ning District, Nanjing, Jiangsu Province, China