【人名反应】Morgan-Walls反应

2022/12/5 18:06:13
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N-酰基邻氨基联苯用POCl3在硝基苯中回流发生闭环脱水而环合成菲啶。

反应机理

反应实例

Morgan-Walls反应是Pictet-Hubert反应的变异，后者的菲啶是由N-酰基邻氨基联苯用ZnCl2加热到250—300℃发生闭环脱水而环合成的

反应实例

参考文献

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7. Holsworth, D. D. Pictet–HubertReaction. In Name Reactions in Heterocyclic Chemistry;

Li, J. J., Ed.; Wiley: Hoboken,NJ, 2005, 465􀀐468. (Review).

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