分子量: 211.26
Cas No.：198835-06-2
结构式：
规格：95%
用途：基础原料、有机中间体、医药中间体
合成路线如下：
diborane;
Reactants are commercially availlable.
Slade, David J., US2011/144150, A1, (2011) In a method analogous to J.Malpass and C. Cox, Tetrahedron Lett., 1999, 40, 1419-1422, tert-butyl 2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate is treated with diborane to afford a mixture of alcohols w hich is separated by chromatography.The desired alcohol tert-butyl 5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate is then oxidized using the Swern procedure to afford the title compound.
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