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名称：(2S,6R)-2,6-二甲基哌啶-4-酮

英文名称：(2S,6R)-2,6-dimethylpiperidin-4-one

分子式：C7H13NO

分子量: 127.18
Cas No.：13200-35-6
结构式：

规格：95%

用途：基础原料、有机中间体、医药中间体

合成路线如下：

hydrogen; ethanol; 5 palladium over charcoal

Reactants are commercially availlable.
ELAN PHARMACEUTICALS, INC., WO2007/64914, A2, (2007) Synthesis of trans-2,6-dimethylpiperidin-4-one (93). trans-N-Benzyl-2,6-dimethylpiperidin-4-one (91; 7.5 g) was dissolved in EtOH (20 mL) and the catalyst (0.8 g, Pd/C 5percent) was added. The slurry was vigorously stirred and kept under a hydrogen atmosphere (60 psi) for 90 hr. The catalyst was rem oved by filtration through Celite and the filtrate was evaporated at 3 mmHg/40 °C. The residue (ca. 5.2 g) was used without further purification.