新闻

名称：1-(Boc-氨基)-3-丁烯
英文名称：tert-butyl but-3-en-1-ylcarbamate
分子式：C9H17NO2

分子量：171.24
Cas No.：156731-40-7
结构式：

规格：95%

用途：基础原料、有机中间体、医药中间体

合成工艺如下：

triethylamine; dichloromethane;

Reactants are commercially availlable.
NOVARTIS PHARMA GMBH, WO2007/48771, A1, (2007) Di-t-butyl dicarbonate (1 equiv) and triethylamine (2.2 equiv) are added subsequently to 3-butene-1 -amine hydrochloride (1 equiv) in CH2CI2. The mixture obtained is stirred in an inert atmosphere for 24 hours at ambient temperature and que nched with an saturated aq. ammonium chloride solution. After extraction with CH2CI2, the combined organic layers obtained are dried, filtered and concentrated. t-Butyl but-3-enyl-carbamate is obtained.